Last Updated: February 8th, 2021

Disclosure: As an Amazon Associate and an affiliate for some reputed brands, I earn from qualifying purchases at no extra cost you. I may recieve a commission if you purchase something mentioned in this post. See more details here.

Sesamoiditis is a painful condition that happens to your big toe.

It can be so painful that it can stop you from walking, running, and your regular day to day activity.

It may get aggravated by continuing to put stress on your feet.

If you still want to run with sesamoiditis, then make sure you have good running shoes.

Any running shoe which is low to zero-drop, shock absorbent, cushy and have a wider toe box should be your go-to shoe.

If you are in dilemma the pick Merrell Women’s Glove 4 Trail Runner.

This is your best option. Otherwise, feel free to choose any of these best women’s running shoes for sesamoiditis.

Our Top Picks

For Trails:

Merrell Women’s Glove 4 Trail Runner

“Suited for any terrain.Best value for money.”

For Roads:

Brooks Women’s Adrenaline GTS 21 Running Shoes

“Great cushioning and knee focused design.”

Best Budget Running Shoes for Overpronation in 2022

Editor Rating:
Merrell Women's Glove 4 Trail Runner

If you are suffering from sesamoiditis, you must have a running shoe which provides you support, should have minimal drop and doesn’t have a toe-bounce. 

Keeping all these in mind, we piked Merrell Women’s Glove 4 Trail Runner.

It is a zero-drop minimalist shoe which has good support and will protect your feet from the harsh terrains.

Also, since it is a minimal shoe it doesn’t have toe-bounce and will also help you to strengthen your feet and toes.

The Vibram out-sole is sturdy enough to even stop rocks and sharp objects on the trails.

Also, it is perfect for running on roads or tracks.

Upper is made from mesh which is very breathable and will keep you cool and comfortable.

It also comes with traditional lacing system and will keep the shoe secure on your feet.

Overall, running in these, you will have a very comfortable experience.

  •   Good for multi-sport.
  •   Highly shock absorbent.
  •   Very durable.
  •   Next best thing to bare foot running.
  •   Zero drop.
  •   Good breathability.
  •   Some felt the quality is not up-to the mark.
  •   Some find the permanent attached tongue is not comfortable.
Editor Rating:

First I would like to clean the air.

This is not a zero drop shoe. In fact, it has a drop of 12 mm.

Why did we select these?

Due to the level of cushioning on the forefoot and the comfort it offers.

Both of these are very much required to ease the pain of sesamoiditis during running.

The softness of the cushion comes from the BioMoGo DNA midsole which is a proprietary material from Brooks.

It also has GuideRails which protects your knees from any kind of impact.

The upper has mesh materials and is very breathable. It keeps you cool and fresh throughout your running session.

Also, the lace-up closure keeps these running shoes fastened securely to your feet all the time.

  •   Good cushioning and support.
  •   Good fore foot cushioning.
  •   Knee focused design.
  •   Good for any kind of feet problem.
  •   May show early signs of wear and tear.
  •   For some the comfort level is lesser than other models from Brooks.
Editor Rating:
Brooks Women's Ariel '18

Ariel is one of the most cushioned running shoe when it comes comfort of your feet.

Also, it is a motion control shoe which will help you with your overpronation.

However, due to the level of cushioning, this is also fantastic for helping you with sesamoditis pain.

It has got wider toe-box and provides you with progressive support when you run or walk.

Also, it is exceptionally good for people with flat to medium arch and comes with a heel clutching system to provide you with more stability.

The mid-sole is made from Super DNA which is 25% more cushy than standard DNA mid-sole.

It comes with no-sew material and keeps your feet irritation free.

Also, do to the breathable top mesh, you get a very healthier in-shoe environment.

The out-sole has blown rubber which gives you proper grip and increases the longevity of this running shoe.

  •   Supportive and super soft cushioning.
  •   Excellent for flat feet.
  •   Lighter than previous version.
  •   You an easily fit your orthotics inside if the need be.
  •   Good for even lower back and leg pain.
  •   Some feels the toe-box is not wide enough.
  •   Some faced with the heel slipping problem.
Editor Rating:
Altra AFW1848G Women's Paradigm 4.0 Running Shoe

This running shoe is perfect if you like zero drop with some cushioning.

The sole is a combination of various technologies and also has Stabilipod.

Stabilipod, essentially works like a tripod by enhancing three natural stability zones of the foot.

This stops your feet from excessive collapse and pronation.

It has the Altra EGO mid-sole which is a dual-nature mid-sole compound with a responsive, yet soft feel for increased energy return.

Also, for people with Sesamoditis, the most beneficial feature of this running shoes is FootShape Toe-Box and FootPod technology.

FootShape allow your toes to spread out naturally and the big-toe remains in a straight position.

Also, with foot pod technology the out-sole actually maps the bones and tendons of your foot to help it bend more naturally.

Overall, you will have an awesome running experience using these shoes and your Sesamoditis will also be at peace.

  •   Very comfortable for flat feet.
  •   FootShape toe-box.
  •   Fit4Her technology for women’s feet.
  •   Zero Drop platform.
  •   FootPod Tehnology for natural bending of feet.
  •   Stabilipod Tehnology for enhanced stability.
  •   Some felt tight at the top of the shoe.
  •   The toe-box seems to be narrower.
Editor Rating:
New Balance Men's 840v4 Running Shoe

This running shoe comes with great shock absorption and this help you to be comfortable while running even if you have sesamoditis.

This extra shock absorption comes from an additional top on the mid-sole called ABZORB.

The mid-sole is made from full length EVA foam, which will give you continuous cushioning.

Also, EVA foam is a very soft and durable foam. This makes these running shoes extremely comfortable and cushy.

The out-sole is made from blown rubber which is very durable.

It protects the mid-sole from wear and tear and lends extra longevity to the shoe.

Also, this is the reason that you have stable grip on the ground. 

The fore foot is segmented giving it additional flexibility and your heel to toe movement becomes effortless.

Also, the upper has engineered mesh and this keeps your feet coo and dry during your workout session.

  •   ABZORB layer for extra shock absorption.
  •   Great for heavier people.
  •   Spacious enough for custom orthotics.
  •   Sole is less stiffer than previous version.
  •   Heel cushioning seems less.
  •   Comfort-ability seems to be lesser than previous version.
Editor Rating:
Vibram Women's V Running Shoe

This is the true barefoot running shoe. You have separate slots to keep each of your toes.

This makes it very comfortable for you as you get that barefoot running feel.

The upper of this running shoe is made from compression material and will not let you have tired feet.

Also, it comes with traditional lace closure and that makes it easier to secure it in place.

There is a pull tab near the Achilles area and this makes it easier or you to wear and take off these five fingers.

The out-sole is of Vibram type and is very tough. This protects you from rocks and sharp objects on your track.

Also, it is very easy to clean these shoes. You just need to machine wash and air dry it.


  •   Barefoot running experience.
  •   Lightweight.
  •   Vibram out-sole for maximum protection.
  •   Lace up closure.
  •   Some felt the quality is not up-to the mark.
  •   Some felt the fit is a bit uncomfortable.


Sesamoiditis can be very painful.

If you don’t take precautions while running, it can cause you serious problem.

Your first and most important line of defense during running is your shoes.

It should be good shock absorbent, low to zero drop and should have a wide toe box.

Based on these criteria, we think Merrell Women’s Glove 4 Trail Runner is the best.

Also, any other shoes from the “best women’s running shoes for sesamoiditis” will also help.

Madhusree Basu

Madhusree Basu

Author, Admin

Blogger and a fitness enthusiast. She loves running and Yoga and everything in between. She started running to manage her weight and to eat to her heart’s content. A true foodie at heart she shares whatever knowledge she has gained throughout the years about weight management and fitness.